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News

  • Cappable-seq Service now available !

    In close cooperation with New England Biolabs, Inc. (NEB), VERTIS is now able to make the new Cappable-seq method available to its customers. The method was developed by Laurence Ettwiller and Ira Schildkraut from NEB (Ettwiller, L. et al. 2016. BMC Genomics. 17, 1 (2016), 199).

    It represents the current most sensitive and robust method for the precise identification of bacterial transcription start sites (TSSs).

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Bioinformatics

Since NGS generates huge quantities of data, bioinformatics is an important task in next generation sequencing projects. VERTIS provides help to their clients to extract maximum information from their experiments. We use CLC Bio's Genomics Workbench software package for data analyses, which incorporates cutting-edge technology and algorithms.

 

Our bioinformatics service covers the following tasks:

Trimming of Reads

  • Barcode filtering
  • Quality, poly(A)+ and adapter trimming of raw sequence data

Mapping and Clustering of Reads

  • De-novo assembly of reads
  • Mapping of reads to reference genomes

RNA-Seq Analysis

  • Digital gene expression (DGE) analysis
  • Identification of transcription start sites (TSSs)
  • MicroRNA analysis
  • Discovery of novel exons
  • Discovery of splice variants

Genome Analysis

  • Identification of SNPs and DIPs (deletion/insertion polymorphisms)
  • Extraction of biding sites and identification of conserved biding motives in Chip-seq experiments
  • Integrated methylation data analysis
 
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